Taking Magnesium for Muscle Pain: Benefits and Recommendations (2025)

Magnesium supplementation significantly reduces muscle soreness post-exercise, enhances recovery and performance, and appears to mitigate muscle damage markers

Taking Magnesium for Muscle Pain Summary

  • With its benefits in lactate buffering, blood glucose maintenance, and muscle cell protection, taking magnesium for muscle pain can useful for athletes and fitness enthusiasts alike.
  • Magnesium supplementation significantly reduces muscle soreness post-exercise, enhances recovery and performance, and appears to mitigate muscle damage markers.
  • The researchers recommended that athletes take a magnesium dosage 10–20% higher than the standard recommended dietary allowance (RDA) for the general population. Specifically, Men: 400–420 mg per day, Women: 310–320 mg daily.
  • The optimal magnesium dose is about 2 hours before exercise.

Taking Magnesium for Muscle Pain: How It Can Help Reduce Soreness and Boost Recovery

Taking Magnesium for Muscle Pain: Benefits and Recommendations (1)When athletes and bodybuilders think about reducing muscle soreness, they often take supplements like EAAs, tart cherry juice, or protein shakes. But one vital mineral is frequently overlooked: taking magnesium for muscle pain. Magnesium is not only essential for general health but may play a significant role in reducing muscle soreness and improving recovery time after intense physical activities.1,2 This understanding comes from a new systematic review titled Effects of Magnesium Supplementation on Muscle Soreness in Different Types of Physical Activities by Maria Grazia Tarsitano, published in the Journal of Translational Medicine in 2024.3 This research, focusing on magnesium’s role in managing muscle pain, has brought valuable insights for athletes seeking optimal recovery and performance.

Why Athletes Need Magnesium More Than Ever

Magnesium deficiency is increasingly common among athletes. Studies estimate that about 22% of international athletes have clinically low magnesium levels, which can negatively impact their performance and recovery.2 Additionally, magnesium plays a role in regulating the inflammatory response, and its deficiency may exacerbate exercise-induced inflammation, further hindering recovery.4

The relationship between magnesium and muscle soreness is particularly relevant for athletes. Following intense exercise, delayed onset muscle soreness is a common experience, and magnesium’s anti-inflammatory properties may help mitigate this condition. Research has shown that magnesium supplementation can reduce markers of muscle damage and inflammation, potentially leading to faster recovery and improved performance.4 Therefore, ensuring adequate magnesium intake may be a critical factor in managing muscle soreness and enhancing recovery for athletes.

Overview of the Study Protocol

Taking Magnesium for Muscle Pain: Benefits and Recommendations (2)The new study by Tarsitano et al. focused on examining the effects of magnesium supplements on muscle soreness and performance across various sports. Researchers analyzed data from several electronic databases, identifying over 1,250 studies related to magnesium and muscle recovery. After screening and narrowing down, four key studies were included. The selected studies involved different types of physical activities and different forms of magnesium supplementation.

Subjects in these studies engaged in various forms of physical training, including resistance exercises like bench presses and endurance activities such as 10-kilometer runs and cycling stages. Participants consumed magnesium in various forms—magnesium oxide, magnesium lactate, and magnesium glycinate—doses ranging from 300 to 500 mg per day. This structured approach allowed the researchers to observe magnesium’s impact across different sports and workout intensities, providing a robust understanding of its effects.

Results: How Magnesium Reduces Muscle Soreness

The study’s results were compelling and consistent across different activities:

Taking Magnesium for Muscle Pain: Benefits and Recommendations (3)Reduced Muscle Soreness: Subjects taking magnesium supplements reported significantly less muscle soreness, particularly 24 to 48 hours post-exercise. This reduction in soreness was seen in both endurance activities, like running, and strength-based exercises, such as bench pressing.

Improved Recovery and Performance: Athletes consuming magnesium showed improved recovery times and felt more ready to train sooner than those without supplementation. For instance, recreational runners experienced reduced post-run muscle soreness and higher post-exercise blood glucose levels, both indicators of enhanced recovery.

Protection Against Muscle Damage: Magnesium was shown to protect against muscle tissue damage, with athletes in endurance sports like cycling and basketball demonstrating fewer markers of muscle stress and damage.

Practical Applications of Taking Magnesium for Muscle Pain

Magnesium is an essential mineral that contributes to numerous physiological processes, including muscle contraction and relaxation, energy metabolism, and the regulation of inflammatory responses. A deficiency in magnesium can lead to increased muscle cramps and spasms, which may exacerbate the perception of muscle soreness after exercise.5

For fitness enthusiasts, taking magnesium for muscle pain can be a simple yet effective way to enhance recovery and reduce soreness. Here are the top ways to make magnesium work for you:

Taking Magnesium for Muscle Pain: Benefits and Recommendations (4)Choose the Right Form: The study revealed that magnesium citrate and glycinate are highly effective for muscle recovery. Citrate is well-absorbed and less likely to cause digestive issues, while glycinate is gentle and offers added calming benefits.

Timing is Key: For the best effects, take magnesium about two hours before training. This timing allows your body to absorb the mineral and have it available when muscles need it most during your workout.

Stick to Recommended Doses: While doses between 300-500 mg were used ins, aim for around 400 mg daily if you’re highly active. Too much magnesium at once can cause digestive discomfort, so consult with a healthcare provider to determine the right dose for you.

Use Off-Season and On-Season Strategies: During the sports season, consider a magnesium supplement to support recovery and endurance. In the off-season, focus on magnesium-rich foods, like nuts and leafy greens, to maintain healthy levels.

References

1 Kharait, S. A Magnesium-Rich Electrolyte Hydration Mix Reduces Exercise Associated Muscle Cramps in Half-Marathon Runners. Journal of Exercise and Nutrition 5 (2022). https://doi.org/10.53520/jen2022.103126

2 Hunt, G., Sukumar, D. & Volpe, S. L. Magnesium and Vitamin D Supplementation on Exercise Performance. Translational Journal of the American College of Sports Medicine 6, e000179 (2021). https://doi.org/10.1249/tjx.0000000000000179

3 Tarsitano, M. G. et al. Effects of magnesium supplementation on muscle soreness in different type of physical activities: a systematic review. J Transl Med 22, 629 (2024). https://doi.org/10.1186/s12967-024-05434-x

4 Erpenbach, K., Erpenbach, M. C., Mayer, W., Hoffmann, U. & Mücke, S. Cellular Magnesium Level and Magnesium Supplementation in Elite Sports: Effect on Mitochondrial Function (ATP), Lactate-Pyruvate- And Muscle-Metabolism (CK). Advances in Orthopedics and Sports Medicine 2021 (2021). https://doi.org/10.37722/aoasm.2021203

5 Bitra, M. & Rajesh, P. Mechanism and Theories for Delayed Onset of Muscle Soreness in Athletes. International Journal of Scientific Advances SP (2021). https://doi.org/10.51542/ijscia.spi1.02

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Taking Magnesium for Muscle Pain: Benefits and Recommendations (2025)
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